Defang is a 6 letter English word. It's valid Words with friends word worth 13 points.
You can make 102 anagrams from letters in defang (adefgn).
First recorded in 1950-55; de- + fang1
There is indeed a threat, but it is the Northern Irish parties themselves who are in the best position to defang it.
It may even sink the talks President Obama is hoping will persuade Iran to defang its nuclear program.
To be sure, Washington has been trying to defang this capability, but it has been living with it.
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