De- is a 3 letter English word. It's valid Scrabble word worth 3 points. It's valid Words with friends word worth 3 points.
You can make 8 anagrams from letters in de- (-de).
Middle English Latin dē-, prefixal use of dē (preposition) from, away from, of, out of; in some words, French Latin dē- or dis- dis-1